Kevin Macdonald is set to direct the whodunit “Murder Mystery,” the first feature from production company Tower Hill Entertainment.

Tower Hill picked up James Vanderbilt’s script from Disney, which put the project into turnaround. Vanderbilt (“Zodiac”) is currently penning the next chapter in Sony’s “Spider-Man” franchise.

Tower Hill is backed by William Shively, an entrepreneur who owns the Florida-based Tower Hill Insurance Group, and Dixiana Farms in Lexington, Ky.

Beau Flynn and Tripp Vinson are producing “Murder Mystery” through their ContraFilm Shingle. Also producing are Vanderbilt and Tower Hill’s A.J. Dix and Shively.

“Murder Mystery” revolves around an American couple honeymooning in Europe who are implicated when they witness a murder and wind up embroiled in international intrigue.

” ‘Murder Mystery’ is pure entertainment. It’s exciting, suspenseful and romantic,” said Dix, who is Tower Hill’s prexy of production.

Dix and Shively founded Tower Hill after leaving shingle FilmEngine, where they they spent 10 years produced titles including “Lucky Number Slevin,” “The Butterfly Effect” franchise and upcoming Johnny Depp-starrer “The Rum Diary.”

Dix said “Murder Mystery” will be shot on location across Europe, and that the film is now casting.

Macdonald, who past credits include “The Last King of Scotland” and “State of Play,” is next in theaters with historical drama “The Eagle of the Ninth,” which Focus Features releases in the U.S. on Sept. 24. Pic stars Channing Tatum, Jamie Bell and Mark Strong.