Michael Eisner will be the keynote speaker at Variety’s upcoming Entertainment and Technology Summit at Loews Santa Monica Hotel.

The former Mouse House chief will kick off the daylong event on Oct. 18, after an intro by Variety publisher Brian Gott.

After exiting Disney in 2005, Eisner launched the Tornante Co., which houses his various production and investment ventures. Among Tornante’s endeavors are the Nick at Nite series “Glenn Martin DDS” and a majority stake in Internet production company Vuguru. Tornante also owns the Topps Co. bubblegum and baseball card manufacturer.

Eisner has just published his third book, “Working Together: Why Great Partnerships Succeed,” profiling successful business partnerships.

Eisner will be joined at the summit by such speakers as Mitch Singer, chief technical officer of Sony Pictures Entertainment; Matt Jacobson, market development head at Facebook; Matt Diamond, CEO of Alloy Media and Marketing; Doug Neil, senior veep of digital marketing at Universal Pictures; and Michael Kassan, CEO of MediaLink.