The three artistic directors of Gotham’s LAByrinth Theater Company, including Philip Seymour Hoffman and John Ortiz, have stepped down from their posts, citing growing professional and family commitments.

Three LAB members — playwright Stephen Adly Guirgis, costume designer Mimi O’Donnell and actor Yul Vazquez — will take up the reins. Hoffman, Ortiz and fellow co-a.d. John Gould Rubin will remain affiliated as members, with Hoffman and Ortiz also serving as board members.

LAB has produced several of Guirgis’ plays, including “Our Lady of 121st Street,” “Jesus Hopped the ‘A’ Train” and “The Last Days of Judas Iscariot.” O’Donnell has worked as a costume designer on multiple LAB stagings, while thesp Vazquez has been a member of the troupe since actor Ortiz (“American Gangster”) co-founded it in 1992.

Hoffman and Ortiz have been co-artistic directors of the LAB for more than a decade. Rubin joined as the third a.d. of the company in 2007.

LAB staffer Marieke Gaboury joins the leadership team as the new producing director.

LAByrinth has been in residence at Off Broadway’s Public Theater for six seasons and is an associate company, with Sydney Theater Company, of London’s Trafalgar Studios.