Nora and Delia Ephron’s stage adaptation of book “Love, Loss and What I Wore” will have a 12-week Off Broadway run beginning in September.

Show will have three casts of five thesps each, including Tyne Daly, Rosie O’Donnell, Kristin Chenoweth and Rita Wilson. Casts will play stints of four weeks each, with exact dates and thesps to be confirmed later.

Production is helmed by Karen Carpenter.

“What I Wore” was first seen in Gotham earlier this year in a series of benefit readings at producer Daryl Roth’s DR2 Theater. Roth also will produce the Off Broadway stint.

Show is based on Ilene Beckerman’s illustrated look at the outfits she wore during different phases of her life. A series of sartorial-themed anecdotes, the legit version takes its inspiration not only from the book but also from personal stories of the Ephrons’ friends.

Production begins previews at the Westside Theater Sept. 21 ahead of an Oct. 1 opening. Some proceeds of the run will go to charity Dress for Success, which provides professional clothes and job support for low-income women.