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“Dawson’s Creek” alum Joshua Jackson is set to appear in several episodes of “Grey’s Anatomy,” while Larenz Tate and Carrie-Anne Moss have been cast in upcoming pilots.

Jackson will play a doctor in a multi-episode arc of “Grey’s,” beginning with this season’s 11th episode. Casting reps Jackson’s return to episodic TV.

Thesp’s recent credits include the upcoming “Shutter,” as well as the 2006 release “Bobby.”

Meanwhile on the pilot front, Moss will play Joseph Fiennes’ wife in “Pretty Handsome,” Ryan Murphy’s FX pilot about a man who realizes he’s a transsexual and undergoes a sex-change operation.

Moss recently appeared in the feature “Disturbia.” Her credits also include “The Matrix” movies.

Thesp joins a cast that also includes Blythe Danner and Robert Wagner. Twentieth Century Fox TV is behind “Pretty Handsome,” which was formerly known as “4 oz.”

Tate is set to play Andre in “Blue Blood,” the NBC police drama from 20th Century Fox TV, Little Engine and Brett Ratner’s Rat Television.

Recently seen in a recurring role on “Rescue Me,” Tate’s credits also include CBS’ short-lived “Love Monkey” and the features “Crash,” “Ray” and “Waist Deep.”