Jessica Biel will topline UA’s crime thriller “Die a Little,” which the studio has set up with Richard Gladstein through his FilmColony banner and Biel’s Iron Ocean Films.

Based on Megan Abbott’s novel, “Die a Little” explores how the lives of a schoolteacher and her LAPD detective brother are turned upside down by a mysterious woman.

The novel’s set in 1954 in the Los Angeles area, but the pic will be set in the present day. Marcia and Geoffrey Blake are writing the script and originally pitched the book-based project.

Gladstein will produce along with Biel and her producing partner Michelle Purple for Iron Ocean, which optioned the book, found the writers and took the project to FilmColony. Neil Parris of FilmColony brought the project in and will exec produce.

Biel, seen most recently in “I Now Pronounce You Chuck and Larry,” is currently in production on “Powder Blue” alongside Forest Whitaker, Patrick Swayze and Ray Liotta.

Gladstein’s credits include “Finding Neverland,” “The Nanny Diaries” and the upcoming “Mr. Magorium’s Wonder Emporium” and “Killshot.”