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PINAMAR, Argentina — Multi-prized Madrid-based helmer Enrique Gabriel is teaming with top-flight Colombian director Victor Gaviria (“The Little Rose Seller”) on what looks set to be Gaviria’s next directorial outing, the immigration-themed “Latinos.”

Set in Spain, “Latinos” follows two Colombian teen brothers who reunite with their mother in Spain and attempt to carve out a new life. One achieves some form of integration, the other remains marginalized.

Gaviria will direct from a screenplay being written by Gabriel, Gaviria and Gabriel’s sister, the screenwriter Masha Gabriel.

Gaviria will produce, while wife Lina Echeverri will take exec producer duties. Film will be produced by Gabriel and Echeverri’s Madrid shingle A.T.P.I.P. Producciones in co-production with a to-be-designated Colombian production house.

“Latinos” will mark a new artistic direction for Gaviria after his high-profile Colombian trilogy turning on violence and streetkids (Cannes competish players “Rodrigo D” and “Rose Seller”) and drug-trafficking (“Additions and Subtractions,” which competed at San Sebastian in 2004).

It marks a creative partnership with Spanish-Argentine helmer-producer Gabriel (“Hitting Bottom,” “Hidden Memories”), who has also won multiple prizes, such as best pic at Karlovy Vary in 1992 for his feature debut “Krapatchouk.”

But, as in other Gaviria pics, “Latino” will use non-pro thesps and be gritty, meticulously researched and long in gestation.

The filmmakers have shot 15 hours of vid interviews with real-life immigrants in Spain, and received some 600 emails from immigrants recounting their experiences, Gabriel said at the Pantalla Pinamar fest in Argentina.

Pic is skedded to shoot December 2007.