Are moviegoers ready for Mel? The biggest wild card at this weekend’s box office is Mel Gibson’s “Apocalypto.” Subtitled pic, set in an ancient Mayan kingdom and sporting extreme violence, skews to an all-male demo. Pic will roll out on 2,465 screens. But the big question is whether the helmer’s offset antics will turn off his fan base. Notices so far have been solid, with talk of an awards season run, and Disney has mounted a concerted PR push to turn attention to the pic and not Gibson’s persona. Gibson’s “The Passion of the Christ” took in more than $370 million domestically in 2004. Meanwhile, women will want in on Columbia romantic comedy “The Holiday,” bowing at 2,610 playdates. Nancy Meyers pic stars Cameron Diaz, Kate Winslet, Jack Black and Jude Law. And Warner Bros. is hoping to gain ground with political action film “Blood Diamond,” from director Ed Zwick and starring Leonardo DiCaprio. Pic bows at 1,900 theaters. Warners also is bowing “Unaccompanied Minors,” a “Home Alone”-like family pic set at an airport.