Odenkirk to captain new HBO laffer

Paybox reteams with 'Mr. Show' star for comedy

HBO has picked up “The Derek & Simon Show,” an improv comedy pilot presentation that reteams the paybox with “Mr. Show with Bob and David” star Bob Odenkirk.

Odenkirk will exec produce alongside Naomi Odenkirk and Brillstein-Grey’s Bernie Brillstein and Tim Sarkes.

Derek Waters and Simon Helberg will star in the half-hour. Odenkirk will direct the pilot.

Show concerns two average guys trying to hook up with women in and around Los Angeles.

Production begins this month. Alternative comedy will be shot in two 15-minutes segments a la “Tenacious D.”

Odenkirk is best known for his HBO sketch series “Mr. Show With Bob and David,” which launched 10 years ago on the paybox. He exec produces the Adult Swim toon “Tom Goes to the Mayor” and will direct the feature comedy “You Are Going to Prison.”Helberg, a former “Mad TV” regular, was featured in the George Clooney/Steven Soderbergh-exec produced HBO skein “Unscripted.”

Waters starred in ABC’s “Married to the Kellys.”