Cameron Diaz will star in “Holiday,” a Sony Pictures Entertainment comedy that Nancy Meyers wrote and will direct this fall.

Pic is Meyers’ follow-up to the Columbia/Warner Bros. co-production “Something’s Gotta Give.” “Holiday” will be the second film under the SPE deal she signed right after Meyers directed the Mel Gibson/Helen Hunt starrer “What Women Want” for Paramount.

“Holiday” is an ensemble romantic comedy with five central characters. Diaz, whose deal is now being negotiated, will play a woman with man trouble until she crosses paths with a woman from a small English village with a similar dilemma. Pic will be overseen by Columbia Pictures exec veep Amy Baer.

Diaz hasn’t been seen onscreen in a while; she will next be seen in the Curtis Hanson-directed “In Her Shoes,” but she backed out of starring with Jim Carrey in the remake of “Fun With Dick and Jane” when that pic’s postponement interfered with her sabbatical plans.

Diaz, who’s expected to once again give the vocals for Princess Fiona in “Shrek 3,” also starred for Columbia in the “Charlie’s Angels” films.