“Frasier” left the building a winner Thursday night, making more than 25 million house calls with its series finale and teaming with “ER” to lift NBC to victory in all key ratings categories.

The most honored program in Emmy history, “Frasier” had lost a step or two by its 11th and final season, but its fans turned out in big numbers for its swan song.

According to Nielsen nationals, the 65-minute “Frasier” finale (8:54-9:59 p.m.) averaged a 9.8 rating/24 share in adults 18-49 and 25.25 million viewers overall — more than double its firstrun season averages and its best scores since October 2000. It beat out some tough competish in CBS drama “CSI” (8.2/20 in 18-49, 22.53m).

Also for NBC, “ER” closed out its season with boffo numbers (11.3/28 in 18-49, 23.88m), up 9% in the demo vs. last season’s finale. Medical drama is poised to edge out “CSI” (9.1 vs. 9.0) and rank as the No. 1 drama in 18-49 for an unprecedented 10th straight year.

NBC won the night over second-place CBS in adults 18-49 (9.1/24 vs. 7.1/19), adults 25-54 (10.3/25 vs. 8.4/20) and total viewers (22.6 million vs. 19.8 million) but the Eye had a solid night as well.

Special “Survivor” seg “America’s Tribal Council” (7.4/21 in 18-49, 19.11m) beat out a “Frasier” clipshow at 8 (5.9/18 in 18-49, 17.93m), nearly matching what regular episodes have been generating in the hour.

And after “CSI” at 9, “Without a Trace” (5.7/14 in 18-49, 17.73m) came in above its season averages opposite the “ER” finale.

ABC grabbed its best adults 18-49 score on a Thursday since Jan. 1 (college football) with the NBA playoff game between the Los Angeles Lakers and San Antonio Spurs (3.5/10 in 18-49, 8.55m).

The Alphabet also had some good ratings news Friday, as “George Lopez” (prelim 2.0/8 in 18-49 with an original episode at 8 and 2.3/8 with a repeat at 8:30) led from 8 to 9 in the demo and the one-hour season finale of “Hope and Faith” followed with a winning demo perf of its own (prelim 2.9/10 in 18-49, 8.2 million).

NBC took the night in 18-49 though (2.6/9), as its two-hour “Dateline” scored a decisive victory at 10 (3.3/11) over ABC’s “20/20” (2.1/7), according to Nielsen prelims.

CBS led Friday in total viewers (prelim 9.1 million), winning each hour, and Fox prevailed in younger demos like persons 12-34 (prelim 2.3/10) with movie “Little Nicky.”

Saturday was another yawner for the nets, with Fox’s combo of “Cops” and “America’s Most Wanted” winning in 18-49 (prelim 2.5/9), NBC’s repeat dramas leading in total viewers (7.6 million) and ABC’s quickie repeat of “Harry Potter and the Sorcerer’s Stone” on top in persons 12-34 (2.1/9).

Also Saturday, NBC’s “Saturday Night Live” (with guest hosts Mary-Kate and Ashley Olsen) matched its second best overnights of the season (7.0/17). It was also its best season finale rating in four years.

And earlier in the day, the net’s coverage of horse racing’s Preakness Stakes (5-6:45 p.m. ET) delivered its highest overnight rating (7.2/16) since 1990, up 29% over last year’s 5.6/13.