NEW YORK — Robin Williams and director Christopher Columbus are in talks to reunite on “Bicentennial Man,” a Nick Kazan-scripted adaptation of an Isaac Asimov short story for Hollywood Pictures, sources said.

A fall start is anticipated for the sci-fi project which is being shepherded by Walt Disney Pictures/Hollywood Pictures prexy David Vogel.

Columbus last directed Williams in the drag comedy “Mrs. Doubtfire” at Fox. Here, the idea is for Williams to play a robot intrigued by humans. It spends two hundred years trying to find what makes a human in the hopes of becoming one.

The film was originally set up at the studio with Wolfgang Petersen attached and with several A-list stars like Tom Hanks intrigued. Petersen dropped out recently, and buzz began to mount about a reteaming of Williams, who just won a supporting actor Oscar for “Good Will Hunting” and Columbus, who recently completed directing the untitled pic formerly known as called “Stepmom,” which stars Julia Roberts and Susan Sarandon.

If talks work out, the plan is to put the film into production this fall for release in late 1999.