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Watch: First Official ‘Scream Queens’ Trailer with Lea Michele & Emma Roberts

The “Scream Queens” have made their official debut.

The first full-length trailer for Ryan Murphy’s upcoming Fox show was released Tuesday, after being teased at Fox’s upfront presentation last week.

Murphy confirmed during upfronts that one of the show leads, who include Lea Michele, Emma Roberts, Jamie Lee Curtis, Abigail Breslin, Keke Palmer and Skyler Samuels, will ultimately be ID’d as the show’s killer who’s been wrecking havoc on a college campus.

“At least one character will be killed off in every episode,” he said.

Nick Jonas and Ariana Grande also recur in the hotly anticipated horror-comedy anthology series — and make their “Scream Queens” debut in the trailer (watch above).

The show 15-episode season is slated to premiere in Sept., airing Tuesdays on Fox’s fall schedule.

“Scream Queens” is exec produced by Murphy, Brad Falchuk, Ian Brennan and Dante Di Loreto.

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