Geena Davis and ARC Entertainment are organizing the event, taking place May 5-9 in the Arkansas city. The actress announced the event in January with the aim of highlighting diversity.
Cannon and producer O’Brien will co-host the festival’s closing-night awards show. O’Brien will also present her new documentary “The War Comes Home.”
The series “Geena and Friends” will reimagine memorable dialogue in the history of cinema. O’Donnell, who co-starred with Davis in “A League of Their Own,” will be among the guests and take part in a panel featuring female celebrities who manage their own film production companies.
De Niro will participate in a discussion following a screening of the documentary “Remembering the Artist,” about De Niro’s father, Robert De Niro Sr.; director Perri Peltz will also participate in the discussion series.
Dern will present the winner of a screenplay competition with $1,500 and a potential 18-month option of the script with Kickstart Productions.
Adams will headline a special “Arkansas in the Biz” panel, moderated by Arkansas Film Commissioner Christopher Crane.
Other than the two documentaries, the festival has not yet announced its lineup of 75 films.