The award will be presented April 22 at CinemaCon in Las Vegas.
The organization noted that he oversaw “Titanic” and “Avatar” — the top-grossing movies of all time — during his tenure at the studio.
Fox has been the top-performing studio this year with “Gone Girl,” “Birdman,” “X-Men: Days of Future Past,” “Dawn of the Planet of the Apes,” “The Fault in Our Stars” and “The Grand Budapest Hotel.”
Fox set a new record this year with more than $5 billion in worldwide receipts.
Gianopulos was previously chairman-CEO of Fox Film Entertainment. Before that, he was president of Twentieth Century Fox International.
Gianopulos sits on both the corporate and foundation boards of the Motion Picture and Television Fund. He has been a long-time supporter of the Pioneers Assistance Fund.
“We are extremely grateful that Jim will accept this well-deserved honor and help raise funds for the Pioneers Assistance Fund,” said Chris Aronson, president of the foundation and president of domestic theatrical distribution of 20th Century Fox.
“He is a leader in our industry with a passion and dedication to the creative process and the desire to assist those who need a helping hand,” Aronson said.
Past honorees include Cecil B. DeMille, Jack Warner, Darryl F. Zanuck, Jack Valenti, Terry Semel, Sumner Redstone, Sherry Lansing, Alan Horn, Kathleen Kennedy, Jeffrey Katzenberg and last year’s honoree, the late Tom Sherak.