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Drew Barrymore and Toni Collette are starring in relationship comedy-drama “Miss You Already,” along with Dominic Cooper, Paddy Considine and Jacqueline Bisset.

Foreign sales at the Toronto Film Festival are being handled by The Salt Company, which shares North American sales with CAA. The film will be distributed in the United Kingdom by Entertainment One.

Production will start in the U.K. on Sunday. Rachel Weisz had previously been attached for Barrymore’s part.

Catherine Hardwicke (“Twilight”) directs from a screenplay by British writer and actor Morwenna Banks (“Damned”). Shooting is largely focused in
London and later moving to the Yorkshire Moors.

Collette and Barrymore portray women who have been best friends forever and Cooper and Considine play their husbands. Bisset portrays the mother of Collette’s character.

The relationship hits a rough patch when Barrymore’s character struggles to have a much longed-for baby and Collette’s character finds out she has breast cancer.

“‘Miss You Already’ explores the ups and down of an intense friendship,” Hardwicke said. “With our fearless actors, we’re taking this very personal story on a wild ride.”

Producers are Christopher Simon and Felix Vossen of Embargo Films. Executive producers are Banks, Hardwicke, Samantha Horley, James Norrie, Barnaby Southcombe, Nicki Hattingh, Anne Sheehan, Sheryl Crown, Lisa Lambert, Celine Rattray and Trudie Styler.

The film is funded by London-based New Sparta Films and Exponential Media.

Barrymore was last seen in “Blended.” Collette stars in “Hector and the Search for Happiness,” which is showing at Toronto as a special presentation.

Considine starred in “Pride,” which debuted at Cannes. Cooper will be seen in “Dracula Untold.”

Bisset stars in “Welcome to New York.”

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