Toni Collette, Danny Huston, Michael Stuhlbarg and Michael Wincott are in negotiations to join the cast of Fox Searchlight’s “Alfred Hitchcock and the Making of ‘Psycho.’”James D’Arcy will play Anthony Perkins and Scarlett Johansson is set to play Janet Leigh, as Variety first reported March 1. Anthony Hopkins stars as Hitchcock in the pic, which follows the iconic helmer’s struggles during the filmmaking of his horror classic “Psycho.” Helen Mirren is set to co-star as Hitchcock’s wife, Alma Reville, while Jessica Biel is in talks to play actress Vera Miles. Collette would play Peggy Robertson, Hitchcock’s longtime assistant; Huston would play Whitfield Cook, Alma’s friend; Stuhlbarg would play Lew Wasserman, Hitchcock’s charismatic agent and Hollywood-savvy friend; and Wincott would play Ed Gein, the serial killer upon whom the “Psycho” book and movie are based. Sacha Gervasi (“Anvil! The Story of Anvil”) is directing from a script by John McLaughlin. Ivan Reitman, Joe Medjuck and Tom Pollack will produce through their Montecito Picture Co. along with Tom Thayer. Collette, who recently co-starred in DreamWorks vampire pic “Fright Night,” just reteamed with her “Muriel’s Wedding” helmer P.J. Hogan on the Aussie dramedy “Mental.” Huston stars on the upcoming Starz series “Magic City,” which was recently renewed for a second season, which sources caution could present a scheduling conflict with “Psycho.” Thesp co-stars as Poseidon in WB’s “Wrath of the Titans.” Stuhlbarg is coming off turns in recent best picture nominees “A Serious Man” and “Hugo.” Thesp will soon be seen in “Men in Black 3″ and Steven Spielberg’s “Lincoln.” Wincott, who’s best known for his lead roles in Alex Proyas’ “The Crow” and Kathryn Bigelow’s “Strange Days,” was last seen in Barry Levinson’s “What Just Happened.” Collette is repped by WME, United Agents, Shanahan Management and attorney Deborah Klein. ICM reps Huston and Stuhlbarg, who are also repped by Julian Belfrage Associates and Viking Entertainment, respectively.