Jaume Collet-Serra is lining up action thriller “Inertia,” starring Oscar Isaac and directed by Gonzalo Lopez-Gallego (“Apollo 18,” “El rey de la montana”).Collet-Serra is producing via his Los Angeles-based Ombra Films, which will team with Miguel Angel Faura’s Roxbury Pictures in Barcelona. Spain’s Film Factory Entertainment has been handling international sales in Berlin. “Inertia” has closed key pre-sales in France (Wildside Films), Russia (Carmen Films), Australia (Vendetta), India (Pictureworks), China, Hong Kong and Taiwan (Pandasia) and the Middle East (Gulf Films), Film Factory’s Vicente Canales said at Berlin. In the Spanish-language “Inertia,” Isaac will limn an immigrant who witnesses a fatal hit-and-run and pursues the car. Lopez-Gallego and his regular scribe Fernando Navarro penned the screenplay. Faura, Collet-Serra and Juan Sola produce. “I’ve been a fan and wanting to work with Gonzalo Lopez-Gallego since ‘El rey de la Montana,’ ” Collet-Serra said. “I’m thrilled that the first film Ombra is doing with Gonzalo will star Oscar Isaac, who I consider to be one of the pre-eminent young actors working today.” Isaac is currently in production on the Coen siblings’ “Inside Llewyn Davis.” “Inertia” is in pre-production, starting principal photography in summer. Ombra Films was launched in 2010 to produce low-budget horror, thriller and fantasy films, often with U.S. stars, but made by Spanish directorial and technical talent. Faura explained that by producing a film in conjunction with the U.S. and with international presales, Roxbury Pictures doesn’t have to depend as much on the market in Spain and Spanish financing. Isaac is managed by Jason Spire at Inspire Ent. and repped by Kevin Volchok at UTA. Ombra Films is repped by Scott Greenberg at CAA.