Peter and Bobby Farrelly will direct and write the project, scheduled for release next year.
Fox exec Jeremy Kramer will oversee the long-gestating project, which the Farrellys originally developed at MGM before it landed at Fox.
Sean Hayes was known for his physical comedy during the “Will & Grace” days, almost a requirement for the slapstick-heavy Stooges.
The plan is to divide the PG-rated film into three, 27-minute segments driven by physical comedy.
Hayes is repped by WME.