Levine to direct movie, which drops old title

Anna Kendrick has signed on to her first film since earning kudos for her breakout role in “Up in the Air.”

The actress will join James McAvoy and Seth Rogen in the untitled Mandate dramedy formerly known as “I’m With Cancer,” which has also found a new helmer in Jonathan Levine (“The Wackness”). He replaces Nicole Holofcener, who dropped out because of personal reasons.

McAvoy toplines as Adam, a 25-year-old who learns he has cancer — a character based on the real-life experiences of Will Reiser, who was diagnosed with cancer in his mid-20s and successfully battled the disease over several years. Reiser wrote the screenplay, which marks his debut feature project.

Kendrick will play a young psychologist assigned to handle Adam’s case despite her lack of experience.

Film begins lensing in next month in Vancouver.

Rogen, Evan Goldberg and Ben Karlin are producing. Reiser is exec producing alongside Mandate prexy Nathan Kahane. Mandate’s Tendo Nagenda is co-producing.

Mandate International will be handling international sales at next month’s European Film Market in Berlin.

Levine is best known for the Gotham-set coming-of-age pic “The Wackness,” which he wrote and directed.

Levine is repped by CAA, the Nervik Co. and attorney Todd Stern.

Kendrick, who most recently earned a Golden Globe nomination for “Up in the Air,” will next be seen in “Scott Pilgrim vs. the World” and “Eclipse,” the third installment in the “Twilight” franchise. Both films are set to be released this year.

Kendrick is handled by CAA and attorney Todd Rubenstein.

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