Wanda Sykes made history this year as the first African-American to emcee the White House Correspondents’ Assn. dinner.Her perf at the lectern received mostly kudos, but she ruffled a few conservative feathers when joking that she hoped Rush Limbaugh’s kidneys would fail. It’s only one of the few times in the recent past where her comic senses have been questioned. Sykes is on a career upswing that includes being host of a new weekly latenight talkshow, which launches Nov. 7 on Fox. “Wanda Sykes is among a small group of comedians who have done films, TV, books and standup and kept a sharp, distinctive voice intact,” says Todd Yasui, Fox’s senior VP of latenight programming. “She cuts to the bone on current issues but, most importantly, she’s damn funny all of the time.” Sykes adds the new job to a schedule that already includes recurring roles on CBS laffer “The New Adventures of Old Christine” and HBO sitcom “Curb Your Enthusiasm.” Meanwhile, the Emmy winner (as a scribe on the “The Chris Rock Show”) recently penned the tome “Yeah, I Said It,” a collection of humorous essays on life and family.