Ryan Murphy, Brad Pitt to produce '4 oz.'

FX has greenlit the pilot episode of Ryan Murphy’s “4 oz.,” and FX and 20th have also picked up three episode scripts.

The unusual and ambitious drama is about the metamorphosis of a man who realizes he is a transsexual.

Series becomes the first to be hatched by the “Nip/Tuck” creator since he signed a multi-year $15 million deal with News Corp.-owned divisions FX, 20th Century Fox and the Fox Network.

Murphy co-created “4 oz.” with “Nip/Tuck” writer Brad Falchuk, and they wrote the pilot together. Murphy, who’ll direct the pilot, will exec produce the FX drama with Brad Pitt and Dede Gardner, with Pitt making his first foray into series TV.

Murphy will begin casting the key role of a married man with two sons whose life takes a radical gender turn.

The series has changed somewhat from the original pitch, which FX prexy John Landgraf bought in the room. The protagonist has been changed from a sportswriter to a gynecologist who shares a medical practice with his father.

Murphy still hopes to stretch the show over several seasons. The first season would deal with the revelation of the doc’s decision; the second would revolve around him transitioning to female; the third would revolve around the surgery, and the fourth would consist of his new life as a woman and his attempt to find love.

“Nip/Tuck” returns in October for its fifth season with Murphy as showrunner.

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