Thesp Prinze toplining ABC laffer

“The Practice” alum Dylan McDermott is plotting his return to TV via the CBS pilot “3 LBS.”

Meanwhile, the WB is aiming high to find its next comedy hit, greenlighting pilots from top producers Jerry Bruckheimer, Imagine TV and Carsey-Werner, while ABC is moving forward with a laffer starring Freddie Prinze Jr.

McDermott will play Dr. Hanson, a top Los Angeles neurosurgeon, in “3 LBS.” Paramount drama comes from Peter Ocko, Paul Stupin, Tom Fontana and Barry Levinson, who is also on board to direct.

“I never thought I would go back to another series this soon, but because of the strength of the script, it was an opportunity I couldn’t pass up,” McDermott said.

Thesp most recently starred in miniseries “The Grid.” He’ll next be seen in the features “Edison,” “Unbeatable Harold” and “The Tenants.”

On the pilot pickup front, the Frog’s untitled Carsey-Werner sitcom also comes from Steve Martin and Joan Stein’s Martin/Stein Co. Female buddy laffer is set in L.A.

Mindy Kaling and Brenda Withers will write and co-exec produce the project, which will be exec produced by Marcy Carsey, Tom Werner, Martin and Stein.

Also, Bruckheimer TV and Warner Bros. TV are behind a WB pilot about three childhood pals who find a female life coach to help them deal with women.

Bruckheimer, Littman and Marsh McCall will exec produce the sitcom, which comes from scribes and co-exec producers Ross McCall and Aaron Peters.

Then there’s the Imagine/20th Century Fox TV pilot, which focuses on a woman whose mother meets the man who was her anonymous sperm donor. Former MGM exec Jeff Kleeman will write, along with Michael Saltzman (“Baby Bob”). Brian Grazer, David Nevins and Saltzman will exec produce.

Over at ABC, Prinze will play a guy who was raised by women — and must adjust when those women move back in with him (Daily Variety, Oct. 27).

Bruce Helford, Deborah Oppenheimer, Bruce Rasmussen and Prinze will exec produce; Helford, Prinze, Conrad Jackson and Rasmussen will write.

John Pasquin is on board to direct the Prinze project.

(Josef Adalian contributed to this report.)

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