Cabler E! is in talks with Loretta Divine (“How Stella Got Her Groove Back”) to take the lead in its first original film, “Best Actress,” after talks last week broke off with Faye Dunaway.Production is scheduled to begin in Vancouver on Sept. 14. Aside from the lead, the rest of the “Best Actress” cast has been set. The film will feature Rachel Hunter, Jamie Presley, Cathy Moriarty, Alicia Donovan, Jordan Ladd, Maria Conchita Alonso and Thomas Calabro. The script was written by Harvey Frost, who adapted John Kane’s book. James Shavick will direct and Lynn Deegan will serve as executive producer.