Comedian joins Pierce, Silver

Warner Bros. has landed Chris Rock to voice “Osmosis Jones,” a streetwise blood cell who’s at the center of the studio’s next major animated feature.

David Hyde Pierce (“Frasier”) will join him as Drix, an inexperienced cold tablet who buddies up with Osmosis to thwart an evil virus out to destroy the body of a construction worker.

WB-based producer Joel Silver — who appeared in the live-action/animation “Who Framed Roger Rabbit” — will voice the police chief; Brandy is negotiating to voice the female lead.

WB’s TV toon strategy

Scripted by Marc Hyman, the pic is being produced by Zak Penn and Dennis Edwards. Tom Sito and Piet Kroon will co-direct.

With “The Iron Giant” bowing Friday, WB has been moving quickly on “Osmosis,” which was greenlit in June and has already been set up at Kids WB with a 13-episode order for an animated TV series to be produced by Warner Bros. TV Animation.

Rock will likely do “Osmosis” before taking his next film-starring job: “I Was Made to Love Her,” the Alphaville-produced Paramount comedy now being rewritten by “American Pie” guys Paul and Chris Weitz, who expect to direct the film in January.

Rock will host the MTV Video Music Awards in September and awaits release of two films: Neil LaBute’s “Nurse Betty,” in which Rock stars with Morgan Freeman and Renee Zellweger; and the Kevin Smith film “Dogma,” which is expected to see release this fall. Rock is repped by ICM and 3 Arts.

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