One of Hollywood’s top femme box office draws, Michelle Pfeiffer, reached an agreement late yesterday to star opposite Jack Nicholson in Columbia Pictures’ “Wolf,” several sources confirmed.

To be directed by Mike Nichols, the picture will begin production in Los Angeles between March 15-April 1.

In development for roughly 18 months, “Wolf” is described as an epic love story about a man’s exploration of his animal spirit.

Director Nichols had been actively casting “Wolf” over the last week. Last year, novelist and screenwriter Jim Harrison was brought in to tailor the “Wolf” screenplay for Nicholson and Pfeiffer.

With Nicholson and Pfeiffer in tow, “Wolf” shapes up as one of Columbia’s major Christmas releases, joining the James Brooks musical “I’ll Do Anything” for the end of 1993. Colpix exec VP of production Amy Pascal was responsible for the development of “Wolf.”

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