Hot Dog Air Force flyer Dennis Quaid is prepared at the outset to be shrunken and pilot a tiny craft through the bloodstream of a laboratory rabbit. Evildoers are on to the unprecedented experiment and the syringe bearing the fearless voyager finally implants itself in the behind of Martin Short, a hapless grocery clerk.
Filmmakers’ ingenuity [screen story by Chip Proser] quickly begins asserting itself. As Quaid travels through different parts of the unsuspecting shnook’s body and speaks to him over his radio, Short believes he’s going crazy before finally accepting what’s happened to him.
Quaid is engagingly reckless and gung-ho as the pioneer into a new dimension, although he is physically constrained in his little capsule for most of the running time. Short has infinitely more possibilities and makes the most of them, coming into his own as a screen personality as a mild-mannered little guy who rises to an extraordinary situation. Meg Ryan is game as the spirited doll both men hanker for, and supporting cast is filled out with a good assortment of familiar faces.
1987: Best Visual Effects